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05/10/2017
NCCN has published updates to the NCCN Guidelines® and the NCCN Compendium® for Bladder Cancer
NCCN has published updates to the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) and the NCCN Drugs & Biologics Compendium (NCCN Compendium®) for Bladder Cancer. These NCCN Guidelines® are currently available as Version 3.2017.
- Principles of Systemic Therapy
- First-line chemotherapy for locally advanced or metastatic disease
- For cisplatin ineligible, “Atezolizumab” was added as a standard option with a category 2A designation for:
- Bladder cancer
- Upper GU tract tumors: Renal pelvis
- Upper GU tract tumors: Urothelial carcinoma of the ureter
- Urothelial carcinoma of the prostate
- Primary carcinoma of the urethra (urothelial carcinomas only)
- For cisplatin ineligible, “Atezolizumab” was added as a standard option with a category 2A designation for:
- Subsequent systemic therapy for locally advanced or metastatic disease
- “Pembrolizumab” was added as a standard regimen option with a category 1 designation for:
- Bladder cancer
- Upper GU tract tumors: Renal pelvis
- Upper GU tract tumors: Urothelial carcinoma of the ureter
- Urothelial carcinoma of the prostate
- Primary carcinoma of the urethra (urothelial carcinomas only)
- “Durvalumab” was added as a standard regimen option with a category 2A designation for:
- Bladder cancer
- Upper GU tract tumors: Renal pelvis
- Upper GU tract tumors: Urothelial carcinoma of the ureter
- Urothelial carcinoma of the prostate
- Primary carcinoma of the urethra (urothelial carcinomas only)
- “Pembrolizumab” was added as a standard regimen option with a category 1 designation for:
- First-line chemotherapy for locally advanced or metastatic disease
*For your reference, the previous update (Version 2.2017) to the NCCN Guidelines for Bladder Cancer, published on February 16, 2017, is available at the following link: https://www.nccn.org/professionals/physician_gls/pdf/bladder.pdf
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